Author: JW Larrick, AR Mendelsohn. Rejuvenation Res. 2012 Oct;15(5):523-9. Dietary restriction (DR), typically a 20%-40% reduction in ad libitum or “normal” nutritional energy intake, has been reported to extend life span in diverse organisms, including…
Author: JW Larrick, AR Mendelsohn. Rejuvenation Res. 2012 Aug;15(4):435-8. The absence of telomerase from somatic cells of mammals has significant consequences for aging. First, it limits the number of potential cell divisions and in so…
Author: JW Larrick, AR Mendelsohn. Rejuvenation Res. 2012 Jun;15(3):334-7. Treatment with rapamycin, an inhibitor of mammalian target of rapamycin complex 1 (mTORC1) can increase mammalian life span. However, extended treatment with rapamycin results in increased…