Neurodegenerative Diseases

Sleep facilitates clearance of metabolites from the brain: glymphatic function in aging and neurodegenerative diseases.

By Aging, ALL, Brain, Neurodegenerative Diseases, Rejuvenation, SleepNo Comments
Author: JW Larrick, AR Mendelsohn. Rejuvenation Res. 2013 Dec;16(6):518-23. Decline of cognition and increasing risk of neurodegenerative diseases are major problems associated with aging in humans. Of particular importance is how the brain removes potentially...
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Rapamycin as an antiaging therapeutic?: targeting mammalian target of rapamycin to treat Hutchinson-Gilford progeria and neurodegenerative diseases.

By ALL, Alzheimer's Disease, Huntington's disease, Hutchinson-Gilford progeria syndrome, Neurodegenerative Diseases, Parkinson's disease, RapamycinNo Comments

Author: JW Larrick, AR Mendelsohn. Rejuvenation Res. 2011 Aug;14(4):437-41. Mammalian target of rapamycin (mTOR), a serine/threonine kinase and component of the mTORC1 signaling complex, acts as an energy, nutrient, growth factor, stress, and redox sensor to…

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