Author: JW Larrick, AR Mendelsohn. Rejuvenation Res. 2015 Apr;18(2):185-7. By maintaining genome integrity, controlling cell proliferation, and regulating tissue homeostasis, telomerase plays a critical role in the pathology of aging and cancer. Telomerase is composed…
Author: JW Larrick, AR Mendelsohn. Rejuvenation Res. 2013 Apr;16(2):152-7. The dysfunctional changes of aging are generally believed to be irreversible due to the accumulation of molecular and cellular damage within an organism’s somatic cells and…
Author: JW Larrick, AR Mendelsohn. Rejuvenation Res. 2012 Aug;15(4):435-8. The absence of telomerase from somatic cells of mammals has significant consequences for aging. First, it limits the number of potential cell divisions and in so…